Asian journal of natural product
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The number of publications is continuously increasing. Yet the annual patent applications worldwide and FDA drug approvals were little changed or not obviously fluctuated in Conclusions: China published the most publications and received the most patent applications, but drug discovery performance is no better than USA and Japan. Research on anti-neoplastic structures and compounds originated from Chinese traditional medicine TCM , medicinal plants, herbal medicine and marine NPs are major research topics in the recent 10 years. There still exits translational gap between basic research and drug discovery. Translational research should be undertaken to strengthen the applicability of NPs. Natural products against cancer: A comprehensive bibliometric study of the research projects, publications, patents and drugs.
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Asian Chemical Editorial Society ACES Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Until now, the top international organic chemistry journals have been either American or European — the Asian Journal of Organic Chemistry AsianJOC is the realization of a dream for organic chemists in Asia. AsianJOC is a top-ranked international research journal with primary publications and critical secondary information from authors across the world.
NMR spectra pointed out the imine bond which is the indicator of the formation of Schiff bases. Besides, antiproliferative and cytotoxic features of the Schiff bases were examined by using MTT cell proliferation and LDH cytotoxicity assays, respectively. Amongst the synthesized Schiff bases, compound 3d exhibited a very strong antiproliferative effect against all cells except A The experimental studies revealed that the Schiff bases synthesized in this study, especially 3d, have an important potential to enter drug development studies. Keywords Amino acid Schiff base, salicylaldehyde, antiproliferative activity, cytotoxicity, anticancer activity References 1.